During a visit to Lichfield Cathedral on the start of the week, King Charles was confronted by a protester who questioned him about his brother's connections with convicted sex offender Jeffrey Epstein.
The individual inquired how long the King had been known about his brother's relationship with Epstein, and also raised doubts about whether he had asked the police to "conceal" for Andrew.
Despite the protest, there were throngs of supporters and applause for the monarch, who was in Staffordshire for an ceremony.
Prince Andrew's associations with Epstein have been under close examination in recent weeks. The prince, who gave up his titles earlier this month, has categorically denied any wrongdoing.
"How long have you been aware about Prince Andrew and Jeffrey Epstein? Have you asked the police to conceal for Andrew?"
The monarch did not respond but continued greeting fans, some of whom chanted "Long live the King". One supporter can be overheard requesting him for a hug.
Another woman outside the cathedral was also heard telling the protester to "go away" and to "be quiet".
The scandal over Prince Andrew's connections to Jeffrey Epstein has been revived by sexual abuse claims repeated in Virginia Giuffre's recently released memoir.
In the memoir, the accuser alleges she had sexual encounters with the royal on three separate occasions, including one instance with Jeffrey Epstein and "eight other young girls"
Andrew, who reached a out-of-court agreement with Ms Giuffre in recent years, has repeatedly denied any misconduct. In a previous interview, he told a news program he did not recall meeting her "at all", and that they "never had any sort of sexual contact."
But in recent times, new inquiries have been asked about how he is able to fund his way of life despite not being a active member of the royal family.
The revelation that he has only ever paid a nominal fee on his Windsor mansion has heightened the examination over his housing situation - even though he made large payments initially, including for improvements.
The political party said he should be called in before MPs to give evidence about his rental agreement of his lodge.
But last week, the authorities declined to give parliamentarians time to debate the prince's status or his home, despite growing pressure for scrutiny.
The royal household has not issued a statement on whether the Duke of York might relocate of his home - or where he might go.
A financial journalist specializing in luxury markets and investment strategies, with over a decade of experience in high-net-worth advisory.